Rhif Cas Acarbose: 56180-94-0 Fformiwla Moleciwlaidd: C25H43NO18
Precos
Precose
prandase
ACARBOSE
Glucobay
bae-g5421
Ascarbose
API Acarbose
Acarbose, 98%
Hydrad Acarbose
Bae g 5421: Glucobay
Acarbose (Acarbosum)
4) -OaD-glwcopyranosyl-(1®
-alffa-d-glwcopyranosyl-(1-4)-
AMylostatin J, Bae g 5421, alffa-GHI
(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-
Acarbose fom Actinoplanes sp.ca.100 FIP-AIU/mg
O-4,6-DIDEOXY-4-[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHY
d-glwcos, o-4,6-dideoxy-4-(((1s-(1-alffa,4-alffa,5-beta,6-alffa))-4,5,6-trihyd
roxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-d-glucopyranosyl-(1-4)-o
4", 6"-Dideoxy-4" - ([1S] -[1,4,6/5] -4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
D-Glwcos, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -aD-glucopyranosyl-(1®
O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D -glwcopyranosyl-(1-4)-O-α-D-glwcopyranosyl-(1-4)-D-Glwcos
4-O-[4-O-[4-[[(1S,4R,5S,6S)-4,5,6-Trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-4 ,6-dideoxy-α-D-glucopyranosyl]-α-D-glucopyranosyl]-D-glwcopyranose
D-Glwcos, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -α-D-glwcopyranosyl-(1→4)-O-α-D-glwcopyranosyl-(1→4)-
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glwcopyranosyl-(1-4)-OaD-glwcopyranosyl-(1-4)-D-glwcos
O-4,6-Dideoxy-4-[[[1S(1α,4α,5β,6α-)-4,5,6-trihydrDxy-3-(hydroxymethyl)-2-cyclohexen-1-y1]amino]- α-D-glwcopyranosyl-(1→4)-O-α-D-ducopyranosyl-(1→4)-D-glwcos
O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -α-D-glwcopyranosyl-(1-4)-O-α-D-glwcopyranosyl-(1-4)-D-glwcos
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5b,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glwcopyranosyl-(1-4)-OaD-glwcopyranosyl-(1-4)-D-glwco-
se
D-Glwcos, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→ 4)-O-α-D-glwcopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]Amino] -ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-ALPHA-D-GLUCOPYRANOSYL-(1-4)-D-GLUCOS
5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]Amino]OXAN-2-YL] OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
Ymdoddbwynt | 165-170°C |
Dwysedd | 1.4278 (amcangyfrif bras) |
tymheredd storio | Awyrgylch anadweithiol, Tymheredd Ystafell 2-8 ° C |
hydoddedd | Hydawdd iawn mewn dŵr, hydawdd mewn methanol, bron yn anhydawdd mewn methylene clorid. |
gweithgaredd optegol | Amh |
Ymddangosiad | Off-Gwyn Solid |
Purdeb | ≥97% |
Dywedir bod Acarbose, oligosaccharid cymhleth sydd wedi'i ynysu o Actinoplanes, yn ddefnyddiol fel therapi cynorthwyol ar gyfer diabetes.Trwy atal alffa-glucosidase, mae acarbose yn gohirio metaboledd carbohydrad yn y llwybr gastroberfeddol ac yn modiwleiddio newidiadau mewn lefelau siwgr yn y gwaed a achosir gan fwyd.
Mae acarbose yn ffug-oligosaccharid gyda therfynell C7-cyclitol a batentiwyd ym 1975 gan Bayer.Mae Acarbose yn rhan o'r cymhleth amylostatin a gynhyrchir gan rywogaethau o Actinoplanes a Streptomyces.Mae Acarbose yn gweithredu fel atalydd cryf o α-glucosidases a sacarasau.Ers 1990, mae acarbose wedi cael ei ddefnyddio'n therapiwtig ar gyfer trin diabetes math 2.
Gofynnwch i'r Meddyg am gyngor yn gyntaf